Harm Reduction — Not Drug Prohibition — Is the Cure for the Opioid Overdose Crisis

Instead of doubling down on War on Drugs policies that aren’t working (and might even be making the problem worse), policymakers should instead embrace harm reduction strategies…

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The U.S. government’s current strategy of trying to restrict the supply of opioids for nonmedical uses is not working. While government efforts to reduce the supply of opioids for nonmedical use have reduced the volume of both legally manufactured prescription opioids and opioid prescriptions, deaths from opioid overdoses are nevertheless accelerating. Research shows the increase is due in part to substitution of illegal heroin for now harder-to-get prescription opioids. Attempting to reduce overdose deaths by doubling down on this approach will not produce better results.

Policymakers can reduce overdose deaths and other harms stemming from nonmedical use of opioids and other dangerous drugs by switching to a policy of “harm reduction” strategies. Harm reduction has a success record that prohibition cannot match. It involves a range of public health options. These strategies would include medication-assisted treatment, needle-exchange programs, safe injection sites, heroin-assisted treatment, deregulation of naloxone, and the decriminalization of marijuana.

Though critics have dismissed these strategies as surrendering to addiction, jurisdictions that have attempted them have found that harm reduction strategies significantly reduce overdose deaths, the spread of infectious diseases, and even the nonmedical use of dangerous drugs.

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Legalizing Marijuana Has Made the Border More Secure

Turns out, legalizing marijuana has done way more for border security than building a wall ever could…

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Although President Trump cites drugs passing over the U.S.’s southern border as a major justification for erecting a border wall, new data shows that, since the legalization of marijuana, drug flow over the border has substantially decreased and fewer drugs are entering where a border wall would matter.

Because it is difficult to conceal, marijuana is the main drug transported between ports of entry where a border wall would matter. However, Border Patrol seizure figures demonstrate that marijuana flows have fallen continuously since 2014, when states began to legalize marijuana. After decades of no progress in reducing marijuana smuggling, the average Border Patrol agent between ports of entry confiscated 78% less marijuana in fiscal year (FY) 2018 than in FY 2013

As a result, the value of all drugs seized by the average agent has fallen by 70% since FY 2013. Without marijuana coming in between ports of entry, drug smuggling activity now primarily occurs at ports of entry, where a border wall would have no effect. In FY 2018, the average inspector at ports of entry made drug seizures that were three times more valuable overall than those made by Border Patrol agents between ports of entry — a radical change from 2013 when Border Patrol agents averaged more valuable seizures. This is because smugglers bring mainly hard drugs through ports. By weight, the average port inspector seized 8 times more cocaine, 17 times more fentanyl, 23 times more methamphetamine, and 36 times more heroin than the average Border Patrol agent seized at the physical border in early 2018.

Given these trends, a border wall or more Border Patrol agents to stop drugs between ports of entry makes little sense. State marijuana legalization starting in 2014 did more to reduce marijuana smuggling than the doubling of Border Patrol agents or the construction of hundreds of miles of border fencing did from 2003 to 2009.

As more states — particularly on the East Coast — legalize marijuana in 2019, these trends will only accelerate. The administration should avoid endangering this success and not prosecute state-legal sellers of marijuana. This success also provides a model for addressing illegal immigration. Just as legalization has reduced the incentives to smuggle marijuana illegally, greater legal migration opportunities undercut the incentive to enter illegally. Congress should recognize marijuana legalization’s success and replicate it for immigration.

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In the War on Drugs, patients and doctors are often the mistaken targets in the fight against the so-called opioid epidemic.

Study after study show a “misuse” rate of less than 1% in patients prescribed opioids for acute pain or chronic pain. And numerous large studies show an even lower overdose rate from opioids used in the medical setting.

Fear of opioids propels drug prohibition, the black market, and rising overdoses from heroin and fentanyl. It also drives the misguided prohibition on prescribing pain medication, causing patients to suffer and destroying lives.

Learn more, and join the conversation on Twitter with #CatoDrugWar…

“Abusedeterrent” Opioids Aren’t the Cure for Overdose Deaths

Could an “abusedeterrent” formulation of OxyContin, introduced in 1996, be to blame for rising overdose deaths?

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Deaths from drug overdoses have steadily increased over the past 15 years — the national death rate (deaths/100,000) for drug poisonings doubled from 1999 to 2014 — and are now at epidemic levels.

Between 1999 and 2009, opioid death rates were rising rapidly, but heroin death rates were much lower and were increasing slowly. In 2010, this changed; over the next four years, heroin death rates increased by a factor of four while opioid death rates remained fairly flat.

The rise in deaths involving heroin or opioids can account for 75% of the overall increase in deaths from drug poisonings.

Opioids are narcotic pain relievers and are available, legally, only by prescription. When used as directed, they are an important element of fighting acute and chronic pain. However, when taken in large quantities, opioids shut down the respiratory system and can lead to death. 

Starting in the mid-1990s, medical groups argued that there was an epidemic of untreated pain, and they urged greater use of opioid pain medicines, especially for those with chronic conditions. The efforts changed prescribing practices considerably. Between 1991 and 2013, opioid prescriptions increased threefold. Opioids are addictive, and as their everyday use increased, so did abuse rates. 

OxyContin became popular for recreational use and abuse because the drug offered much more of the active ingredient, oxycodone, than other prescription opioids, and because the pills could easily be manipulated to access the entire store of the active ingredient. In early August 2010, the makers of OxyContin, Purdue Pharma, took the existing drug off the market and replaced it with an abusedeterrent formulation (ADF) that made it difficult to abuse the drug in this fashion.

OxyContin prescriptions, deaths from opioids, fatalities reported to the makers of OxyContin, calls to poison control centers for opioids, and entrance into opioid treatment programs all have flatlined since the third quarter of 2010. 

However, this change made the drug far less appealing to opioid abusers and led many to shift to a readily available and cheaper substitute, heroin.

The Food and Drug Administration has promoted the development of abuse-deterrent opioids, like the one created for OxyContin, to pharmaceutical companies and has worked with manufacturers to bring these products to market as quickly as possible. Most recently, the Food and Drug Administration listed the development of ADFs as a national policy priority, 5 states have adopted laws requiring insurance companies to cover ADFs, and similar laws have been proposed in 15 other states

However, the evidence is clear that these policies don’t work

For example, in the case of the OxyContin reformulation, opioid death rates were increasing rapidly across all groups before reformulation, but were flat afterward. That might seem like a success, but when heroin and opioid death rates are combined, there’s no evidence that total heroin and opioid deaths fell at all after the reformulation. Instead, there appears to have been one-for-one substitution of heroin deaths for opioid deaths.

Thus, it appears that the intent behind the abuse-deterrent reformulation of OxyContin was completely undone by changes in consumer behavior.

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Do Legal Marijuana Dispensaries Cause Crime?

60% of U.S. adults favor broad-based marijuana legalization, but 44% would be concerned if a medical marijuana dispensary opened in their area. This discrepancy comes from the belief that dispensaries attract crime. Do they?

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The idea that marijuana dispensaries attract crime has proved influential with policymakers. Yet, empirical evidence to support any link between marijuana dispensaries and crime is quite limited.

In Los Angeles, for example, the city council cited crime in its 2010 decision to cap the number of dispensaries in the city. On June 7, 2010, roughly 70% of the nearly 600 shops operating in the City of Los Angeles were ordered to close. The shutdown came after years of concern and indecision over how to handle the burgeoning medical marijuana dispensary business in the city. In September 2007, the city adopted an Interim Control Ordinance, placing a temporary moratorium on new dispensaries and requiring existing dispensaries to register with the city by November 13, 2007.

Given the limited time that dispensaries had to submit a registration form along with the required city business tax registration certificate, registration was quite ad hoc. How the city would use the registrations was unclear, and the market continued to grow for several years despite the moratorium. In January 2010, final regulations, including closure orders, were adopted. The new ordinance set the number of dispensaries in the city at 70. Dispensaries that had registered between September and November 2007 and had been operating legally since that time were grandfathered, meaning that the number of legal dispensaries in the city could exceed 70 in the short term.

Closure orders were not correlated with observable dispensary characteristics (including the level of or trend in crime around specific dispensaries) that might have otherwise made them of specific interest to law enforcement. 

Contrary to conventional wisdom, there is no evidence that closures decreased crime. Instead, there was a significant relative increase in crime around closed dispensaries. Like compliance with the closure orders themselves (which was at first high, then fell off with legal challenges, and finally collapsed after a December 2010 injunction), the increase in crime is temporary. Relative crime rates return to normal within four weeks. The increase is also very local—the estimated crime effects decrease rapidly with distance around dispensaries.

Closing medical marijuana dispensaries is unlikely to reduce crime. Rather, the presence of individuals — including those brought to an area by marijuana businesses — helps deter crime.

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The War on Drugs Fails Again

El Chapo’s capture created a power vacuum, intensifying the violent chaos in Mexico, with deaths at a record high…

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Both Mexican and U.S. officials basked in satisfaction when Mexican marines captured Joaquin “El Chapo” Guzman Loera, leader of the notorious Sinaloa drug cartel, in January 2016. The cartel kingpin was subsequently extradited to the United States.

Authorities on both sides of the Rio Grande heralded El Chapo’s removal as a major victory in the war on illegal drugs, but matters have not turned out at all the way drug warriors and other optimists assumed. 

El Chapo’s capture has made the violent chaos in Mexico worse—much worse.

Under Guzman’s leadership, the Sinaloa cartel became Mexico’s most powerful drug trafficking operation, controlling nearly 50% of drug commerce. Although considerable violence accompanied that consolidation of market share, as the Sinaloa organization’s grip on the trade grew tighter, the turmoil ebbed modestly after 2012.

That encouraging trend has now sharply reversed.

El Chapo’s fall created a power vacuum throughout Mexico’s ruthless drug trade. The extent of the upsurge in violence as his would-be successors maneuver for control is horrifying.

Killings began to edge upward in 2015 when Guzman was briefly in custody following more than a decade of freedom after his original escape in January 2001, dipped slightly when he escaped again, and rose noticeably with his recapture and extradition.

In May alone, there were 2,186 fatalities — the third time in 2017 when the monthly death toll topped 2,000. That is more than twice the average monthly pace of the bloody years of Felipe Calderon’s presidency (2006-2012), when more than 60,000 Mexicans perished in drug-related carnage.

The May total was a new record, and it brought the total number of deaths in 2017 to 9,906. That was an increase of 33% over 2016, which had already seen a worrisome rise.

The current drug war policies that Washington has pushed and Mexico City has accepted is creating havoc for our southern neighbor.

When there is a profitable market for a product, government policy can determine whether legitimate businesses will fill that demand — or whether criminal gangs will do so.

Punitive measures will not succeed in eliminating consumer demand or overcome other economic realities. Cartel leaders and their bank accounts may benefit from that policy, but no one else on either side of the Rio Grande is doing so. 

Capturing or killing one drug lord — even an extraordinarily powerful one like El Chapo — will not ameliorate the problem in any significant or lasting sense. All such “victories” do is unleash bloody struggles for succession.

U.S. and Mexican authorities need to abandon the disastrous prohibition policy, and move toward a legalized system for drug commerce, thereby undercutting the power of the cartels. Otherwise, Mexico’s agony will become even worse, and the chaos will spill over the border into the United States.

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Synthetic Drugs Are Very Dangerous. Let’s Legalize Them.

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Originally posted by randilynn426

Lately, the media has been in a tizzy about synthetic or “designer” drugs. These produce physical and psychological effects similar to traditional, mind-altering substances like marijuana, cocaine and heroin. But they’re different in a crucial way. Not only are they frequently marketed as potpourri, pet food, air freshener and other legal products, but because they are artificial substances, even a slight change in the chemical composition can make the targeted drug no longer covered by existing law.

Here’s why they should be LEGAL….

This week in the Cato Weekly Dispatch….

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We take a sneak peek at what’s next in the fight against unconstitutional NSA spying, explore a dangerous but growing trend caused by our failed Drug War policies, get the inside scoop on the dehumanizing life of an inmate from a former Department of Corrections Commissioner turned felon, and more…

Take a look for yourself…..

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Loretta Lynch Confirmed as Attorney General

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After one of the longest confirmation processes in the history of the Attorney General’s office, Loretta Lynch was confirmed by the Senate today as Eric Holder’s successor. From a criminal justice perspective, whether Lynch will embrace or abandon Holder’s position on state-level drug legalization and his announced commitment to reforming civil asset forfeiture are two questions that spring immediately to mind.

“America has a new Attorney General, but precisely what that means for federal criminal justice reform remains an open question,” says Cato policy analyst Adam Bates.