Harm Reduction — Not Drug Prohibition — Is the Cure for the Opioid Overdose Crisis

Instead of doubling down on War on Drugs policies that aren’t working (and might even be making the problem worse), policymakers should instead embrace harm reduction strategies…

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The U.S. government’s current strategy of trying to restrict the supply of opioids for nonmedical uses is not working. While government efforts to reduce the supply of opioids for nonmedical use have reduced the volume of both legally manufactured prescription opioids and opioid prescriptions, deaths from opioid overdoses are nevertheless accelerating. Research shows the increase is due in part to substitution of illegal heroin for now harder-to-get prescription opioids. Attempting to reduce overdose deaths by doubling down on this approach will not produce better results.

Policymakers can reduce overdose deaths and other harms stemming from nonmedical use of opioids and other dangerous drugs by switching to a policy of “harm reduction” strategies. Harm reduction has a success record that prohibition cannot match. It involves a range of public health options. These strategies would include medication-assisted treatment, needle-exchange programs, safe injection sites, heroin-assisted treatment, deregulation of naloxone, and the decriminalization of marijuana.

Though critics have dismissed these strategies as surrendering to addiction, jurisdictions that have attempted them have found that harm reduction strategies significantly reduce overdose deaths, the spread of infectious diseases, and even the nonmedical use of dangerous drugs.

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Legalizing Marijuana Has Made the Border More Secure

Turns out, legalizing marijuana has done way more for border security than building a wall ever could…

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Although President Trump cites drugs passing over the U.S.’s southern border as a major justification for erecting a border wall, new data shows that, since the legalization of marijuana, drug flow over the border has substantially decreased and fewer drugs are entering where a border wall would matter.

Because it is difficult to conceal, marijuana is the main drug transported between ports of entry where a border wall would matter. However, Border Patrol seizure figures demonstrate that marijuana flows have fallen continuously since 2014, when states began to legalize marijuana. After decades of no progress in reducing marijuana smuggling, the average Border Patrol agent between ports of entry confiscated 78% less marijuana in fiscal year (FY) 2018 than in FY 2013

As a result, the value of all drugs seized by the average agent has fallen by 70% since FY 2013. Without marijuana coming in between ports of entry, drug smuggling activity now primarily occurs at ports of entry, where a border wall would have no effect. In FY 2018, the average inspector at ports of entry made drug seizures that were three times more valuable overall than those made by Border Patrol agents between ports of entry — a radical change from 2013 when Border Patrol agents averaged more valuable seizures. This is because smugglers bring mainly hard drugs through ports. By weight, the average port inspector seized 8 times more cocaine, 17 times more fentanyl, 23 times more methamphetamine, and 36 times more heroin than the average Border Patrol agent seized at the physical border in early 2018.

Given these trends, a border wall or more Border Patrol agents to stop drugs between ports of entry makes little sense. State marijuana legalization starting in 2014 did more to reduce marijuana smuggling than the doubling of Border Patrol agents or the construction of hundreds of miles of border fencing did from 2003 to 2009.

As more states — particularly on the East Coast — legalize marijuana in 2019, these trends will only accelerate. The administration should avoid endangering this success and not prosecute state-legal sellers of marijuana. This success also provides a model for addressing illegal immigration. Just as legalization has reduced the incentives to smuggle marijuana illegally, greater legal migration opportunities undercut the incentive to enter illegally. Congress should recognize marijuana legalization’s success and replicate it for immigration.

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In the War on Drugs, patients and doctors are often the mistaken targets in the fight against the so-called opioid epidemic.

Study after study show a “misuse” rate of less than 1% in patients prescribed opioids for acute pain or chronic pain. And numerous large studies show an even lower overdose rate from opioids used in the medical setting.

Fear of opioids propels drug prohibition, the black market, and rising overdoses from heroin and fentanyl. It also drives the misguided prohibition on prescribing pain medication, causing patients to suffer and destroying lives.

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Ending the War on Drugs Would Be a Budgetary Boon

Ending the War on Drugs could generate up to $106.7 billion in annual budgetary gains for federal, state, and local governments

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In the past several years, the national movement to end drug prohibition has accelerated. Nine states and Washington, DC, have legalized recreational marijuana, with at least three more states (Connecticut, Michigan, and Ohio) likely to vote on legalization by the end of 2018. Dozens of others have decriminalized the substance or permitted it for medicinal use. Moreover, amid the nation’s ongoing opioid crisis, some advocates and politicians are calling to decriminalize drugs more broadly and rethink our approach to drug enforcement.

Drug legalization affects various social outcomes. In the debate over marijuana legalization, academics and the media tend to focus on how legalization affects public health and criminal justice outcomes. But policymakers and scholars should also consider the fiscal effects of drug liberalization.

Legalization can reduce government spending, which saves resources for other uses, and it generates tax revenue that transfers income from drug producers and consumers to public coffers.

Drawing on the most recent available data, drug legalization could generate up to $106.7 billion in annual budgetary gains for federal, state, and local governments. Those gains would come from two primary sources: decreases in drug enforcement spending and increases in tax revenue. State and local governments spend around $29 billion on drug prohibition annually, while the federal government spends an additional $18 billion. Meanwhile, full drug legalization would yield $19 billion in state and local tax revenue and $39 billion in federal tax revenue.

In addition, the budgetary effects of state marijuana legalizations that have already taken place in Colorado, Oregon, and Washington have been positive. So far, legalization in those states has generated more tax revenue than previously forecast but generated essentially no reductions in criminal justice expenditure. 

At both the federal and state levels, government budgets would benefit enormously from drug legalization policies. 

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Doubling Down on the Drug War Will Only Make the Opioid Crisis Worse

The United States has seen a surge in deaths from overdoses of opioids, including both prescription drugs and illegal opioids such as heroin. Unfortunately, the policy “cures” have uniformly worsened the problem...  

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It is simplistic—and thus provides an easy target—for politicians and the media to latch on to the false narrative that greedy pharmaceutical companies teamed up with lazy, poorly-trained doctors, to hook innocent patients on opioids and condemn them to a life of drug addiction. But this has never been the case.

Despite the fact that the government’s own numbers have shown for years that the overdose crisis is primarily the result of nonmedical users seeking drugs in the black market created by drug prohibition, policymakers seem intent on seeing doctors treating patients in pain as the source of the opioid overdose crisis. And their focus has been on getting doctors to curtail prescribing opioids.

As prescriptions continue to decrease, overdose deaths continue to increase. This is because as non-medical users get reduced access to usable diverted prescription opioids, they migrate to more dangerous fentanyl and heroin.

Meanwhile, a lot of patients, in and out of the hospital, suffer from under-treatment of pain. 

The DEA, which sets national manufacturing quotas for opioids, ordered a 25% reduction in 2017 & 20% again this year. As a result, hospitals across the country are facing shortages of injectable morphine, fentanyl, and Dilaudid (hydromorphone), and trauma patients, post-surgical patients, and hospitalized cancer patients frequently go undertreated for excruciating pain. The shortage is uneven across the country. Some hospitals are feeling the shortage worse than others, but it’s clear that the “war on opioids” being waged by today’s policymakers is, in effect, a “war on patients in pain.”

Hospitals are working hard to ameliorate the situation by asking medical staff to use prescription opioid pills such as oxycodone and OxyContin instead of injectables, but many patients are unable to take oral medication due to their acute illness or post-operative condition. In those cases, hospitals use injectable acetaminophen, muscle relaxants, or non-steroidal anti-inflammatory agents, but those drugs fail to give adequate relief.  Some hospitals have even resorted to asking nursing staff to manually combine smaller-dose vials of morphine or other injectable opioids that remain in-stock as a replacement for the out-of-stock larger dose vials. Dose-equivalents of different IV opioids vary and are difficult to accurately calculate. This increases the risk of human error and places patients at risk for overdose.

In another misguided attempt to reduce opioid use, abuse, and overdoses, policymakers have also focused on developing and promoting tamper-resistant or abuse-deterrent formulations (ADFs) that render diverted opioids unusable if individuals attempt to use them for nonmedical purposes.

Although the benefits of ADFs seem to be nonexistent, these formulations have led to real harms. ADFs have encouraged users to switch to more dangerous opioids, including illegal heroin. In at least one instance, the reformulation of a prescription opioid led to a human immunodeficiency virus (HIV) outbreak. Along the way, ADFs unnecessarily increase drug prices, imposing unnecessary costs on health insurance purchasers, taxpayers, and particularly patients suffering from chronic pain.

Meanwhile, the CDC’s methods for tracking opioid overdose deaths have over-estimated the number of those deaths due to prescription opioids, as opposed to heroin, illicitly manufactured fentanyl, and other illicit variants of fentanyl. The exact drugs involved in overdose deaths are not identified in 20% of death certificates, multiple drugs are involved in over half of their reported cases of prescription opioid overdoses, and the number of deaths due to diverted (stolen, smuggled, or sold by dealers) prescription opioids is unknown. 

If policymakers are serious about wanting to reduce overdose deaths, they should look to what has been done in Portugal, and now Norway, and end the war on drugs.

Unfortunately, the Trump Administration’s response has been disappointing at best. 

President Trump sees the zero-tolerance policies of Singapore, China and the Philippines as a model for U.S. drug policy. Even worse, Trump is said to believe that all drug dealers should get the death penalty.

The president’s frustration with the failure of the war on drugs is understandable. But the solution should not be to try more of the same, only “tougher.” Threats of increased prisons sentences — or even death sentences — amount to nothing more than a temper tantrum.

Sensible drug policy makes it easier for people with substance abuse problems to transition back to a normal life, rather than ruining their lives through long-term incarceration — or ending them altogether through capital punishment.  If the goal is reducing drug-related deaths, policymakers should put more emphasis on “harm reduction” measures, such as syringe services programs, medication-assisted treatment with drugs such as methadone, buprenorphine, or naltrexone, and enhanced distribution of naloxone, the antidote for an opioid overdose. These programs not only reduce deaths but are a more cost-effective allocation of resources.

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Another Misstep in the Federal War on Drugs

“Abuse-deterrent” opioids have done nothing to address the surge in deaths from opioid overdoses — but they have made the problem much worse…

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The United States has seen a surge in deaths from overdoses of opioids, including both prescription drugs and illegal opioids such as heroin. Nonmedical users and abusers often obtain prescription opioids diverted from the legal to the illegal market. In the hope of reducing opioid use, abuse, and overdoses, policymakers have focused on developing and promoting tamper-resistant or abuse-deterrent formulations (ADFs) that render diverted opioids unusable if individuals attempt to use them for nonmedical (i.e., recreational) purposes.

In other words, the government is adding poison to prescription opioids to “discourage” recreational use, just as they once distributed poisoned alcohol during Prohibition to “discourage” recreational use.  Unsurprisingly, it is making the “opioid epidemic” far, far worse… 

Although the benefits of ADFs seem to be nonexistent, these formulations have led to real harms. ADFs have encouraged users to switch to more dangerous opioids, including illegal heroin. In at least one instance, the reformulation of a prescription opioid led to a human immunodeficiency virus (HIV) outbreak. Along the way, ADFs unnecessarily increase drug prices, imposing unnecessary costs on health insurance purchasers, taxpayers, and particularly patients suffering from chronic pain. Like the federal government’s promotion of abuse-deterrent alcohol a century ago, these efforts are producing unintended consequences, such as making legal pain relief unaffordable for many patients and possibly increasing morbidity and mortality.

Government at all levels should stop promoting ADF opioids. Congress should end or limit the ability of pharmaceutical manufacturers to impose higher costs on pain patients by using ADFs to “evergreen” their opioid patents (evergreening is a practice by which pharmaceutical manufacturers extend or renew the patent protection before the current patent expires by tweaking the formula slightly or repurposing the product)/

The FDA should end its policy of encouraging ADF opioids and particularly its goal of eliminating non-ADF opioids. Lawmakers should abandon efforts to require consumers to purchase coverage for costlier ADF opioids and should instead allow insurers to steer medical users of these products toward cheaper, non-ADF generic formulations.

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Legal Marijuana Under Attack

The DOJ is using the criminal law to trample on state prerogatives and individual rights…

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Today, Attorney General Sessions announced that the Department of Justice rescinded the “Cole Memo,” an internal enforcement guideline from the Obama Administration that de-prioritized enforcement of federal marijuana prohibition against individuals and businesses complying with state laws regarding recreational marijuana. This move endangers state-legal businesses and violates the principles of federalism that have been central to the Republican Party for decades.

This was made possible, in part, by the failure of the judiciary to rein in the power of an overzealous federal government. The Supreme Court has twice approved of this type of overreach. In Wickard v. Filburn (1942) and Gonzales v. Raich(2005), the Court ruled that individuals growing crops exclusively for personal consumption—wheat and marijuana, respectively—could be regulated by the interstate commerce clause of the U.S. Constitution despite the crops never entering a market of any kind, let alone across state lines.

While the average marijuana consumer is not going to be targeted or arrested by the federal government, business owners directly and indirectly involved in state-legal recreational marijuana distribution may see their freedoms and livelihoods threatened by this action.  Put simply, the DOJ is using the criminal law to trample on state prerogatives and individual rights. 

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Do Legal Marijuana Dispensaries Cause Crime?

60% of U.S. adults favor broad-based marijuana legalization, but 44% would be concerned if a medical marijuana dispensary opened in their area. This discrepancy comes from the belief that dispensaries attract crime. Do they?

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The idea that marijuana dispensaries attract crime has proved influential with policymakers. Yet, empirical evidence to support any link between marijuana dispensaries and crime is quite limited.

In Los Angeles, for example, the city council cited crime in its 2010 decision to cap the number of dispensaries in the city. On June 7, 2010, roughly 70% of the nearly 600 shops operating in the City of Los Angeles were ordered to close. The shutdown came after years of concern and indecision over how to handle the burgeoning medical marijuana dispensary business in the city. In September 2007, the city adopted an Interim Control Ordinance, placing a temporary moratorium on new dispensaries and requiring existing dispensaries to register with the city by November 13, 2007.

Given the limited time that dispensaries had to submit a registration form along with the required city business tax registration certificate, registration was quite ad hoc. How the city would use the registrations was unclear, and the market continued to grow for several years despite the moratorium. In January 2010, final regulations, including closure orders, were adopted. The new ordinance set the number of dispensaries in the city at 70. Dispensaries that had registered between September and November 2007 and had been operating legally since that time were grandfathered, meaning that the number of legal dispensaries in the city could exceed 70 in the short term.

Closure orders were not correlated with observable dispensary characteristics (including the level of or trend in crime around specific dispensaries) that might have otherwise made them of specific interest to law enforcement. 

Contrary to conventional wisdom, there is no evidence that closures decreased crime. Instead, there was a significant relative increase in crime around closed dispensaries. Like compliance with the closure orders themselves (which was at first high, then fell off with legal challenges, and finally collapsed after a December 2010 injunction), the increase in crime is temporary. Relative crime rates return to normal within four weeks. The increase is also very local—the estimated crime effects decrease rapidly with distance around dispensaries.

Closing medical marijuana dispensaries is unlikely to reduce crime. Rather, the presence of individuals — including those brought to an area by marijuana businesses — helps deter crime.

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The Hydra-Headed Drug Business

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With television cameras rolling and Attorney General Jeff Sessions on hand in San Diego, the Coast Guard announced late last month that it had set a new record for cocaine seizures at sea—more than 455,000 pounds through September 11, topping last year’s record.  

At last we’ve turned the corner in the war on drugs. Right?

Don’t bet on it. When Americans read about ever-larger drug busts, or when we watch television shows about drug enforcement, we get the impression that drug enforcement agents are clever and innovative, always staying one step ahead of the sinister pushers. But in reality the drug distributors are the innovative ones—because they have a financial incentive to be.

That’s why we keep reading the same story.

Learn more in a blog post by Cato’s David Boaz…

The War on Drugs Fails Again

El Chapo’s capture created a power vacuum, intensifying the violent chaos in Mexico, with deaths at a record high…

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Both Mexican and U.S. officials basked in satisfaction when Mexican marines captured Joaquin “El Chapo” Guzman Loera, leader of the notorious Sinaloa drug cartel, in January 2016. The cartel kingpin was subsequently extradited to the United States.

Authorities on both sides of the Rio Grande heralded El Chapo’s removal as a major victory in the war on illegal drugs, but matters have not turned out at all the way drug warriors and other optimists assumed. 

El Chapo’s capture has made the violent chaos in Mexico worse—much worse.

Under Guzman’s leadership, the Sinaloa cartel became Mexico’s most powerful drug trafficking operation, controlling nearly 50% of drug commerce. Although considerable violence accompanied that consolidation of market share, as the Sinaloa organization’s grip on the trade grew tighter, the turmoil ebbed modestly after 2012.

That encouraging trend has now sharply reversed.

El Chapo’s fall created a power vacuum throughout Mexico’s ruthless drug trade. The extent of the upsurge in violence as his would-be successors maneuver for control is horrifying.

Killings began to edge upward in 2015 when Guzman was briefly in custody following more than a decade of freedom after his original escape in January 2001, dipped slightly when he escaped again, and rose noticeably with his recapture and extradition.

In May alone, there were 2,186 fatalities — the third time in 2017 when the monthly death toll topped 2,000. That is more than twice the average monthly pace of the bloody years of Felipe Calderon’s presidency (2006-2012), when more than 60,000 Mexicans perished in drug-related carnage.

The May total was a new record, and it brought the total number of deaths in 2017 to 9,906. That was an increase of 33% over 2016, which had already seen a worrisome rise.

The current drug war policies that Washington has pushed and Mexico City has accepted is creating havoc for our southern neighbor.

When there is a profitable market for a product, government policy can determine whether legitimate businesses will fill that demand — or whether criminal gangs will do so.

Punitive measures will not succeed in eliminating consumer demand or overcome other economic realities. Cartel leaders and their bank accounts may benefit from that policy, but no one else on either side of the Rio Grande is doing so. 

Capturing or killing one drug lord — even an extraordinarily powerful one like El Chapo — will not ameliorate the problem in any significant or lasting sense. All such “victories” do is unleash bloody struggles for succession.

U.S. and Mexican authorities need to abandon the disastrous prohibition policy, and move toward a legalized system for drug commerce, thereby undercutting the power of the cartels. Otherwise, Mexico’s agony will become even worse, and the chaos will spill over the border into the United States.

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